Endocrine Abstracts

Fasting hypoglycemia in the setting of hyperinsulinemia typically is persistent and often progressive. We present a case where fasting hypoglycemia with hyperinsulinemia was transient in nature over a fortnight. This occurred in the setting of recurrent seizure-like activity. Seizures are a well known sequela of hypoglycemia; however, the reverse is not nearly as well documented. A 20 year old male with a history of developmental delay, chronic PEG tube, and nonverbal at basel...

Introduction: We present a case of a patient with type two diabetes mellitus (T2DM) who started empagliflozin, a sodium-glucose cotransporter-2 (SGLT2) inhibitor and the P90X diet and presented with euglycemic DKA seven days later.Case Presentation: A male in his 5th decade of life with a history of T2DM presented for a routine office appointment and had a measured hemoglobin A1C of 9.3. His home diabetes regimen consisted of metformin and sitagliptan. D...

Denosumab is a monoclonal antibody used in the treatment of osteoporosis to prevent bony injuries by increasing bone density. It does so by binding to RANK-L, which is then unable to activate RANK, thereby preventing osteoclast maturation and viability. Although rare, the effect of denosumab can interfere with the body’s calcium homeostasis and lead to a hypocalcemic state. We present a case where a post-menopausal female developed severe, symptomatic hypocalcemia from a...